RevitaLife COMPOUNDING PHARMACY

Weight management has become an important aspect of an active and healthy lifestyle. As the obesity rates continue to rise, apart from nutrition and exercise, many factors play a role in weight management including several hormonal imbalances.

We recognize the importance of using evidence-based methods and offer a range of compounding solutions for weight management:

Lipotropic agents / Vitamin Therapies – vitamins and amino acids can be use to stimulate the utilization of fat reserves as an energy source for weight management and to provide essential micronutrients at the same time. These include:

  • B12 injectables as a bioactive form Hydroxocobalamin or Methylcobalamin form.
  • Methionine, Inositol and Choline (MIC) injectables or MIC Combinations that contain amino acid Methionine and vitamins of the B family including Inositol and Choline. A combination of these components sits in utilization of body fat as an energy source and prevents the storage of excess energy as fat.
  • Pyridoxine (B6) Injection
    Vitamin B6 stimulates the thyroid gland and reduces the incidence of water retention in the body. In an event of limited calorie intake, Vitamin B6 helps in the conversion process of complex carbohydrates to glucose in order to maintain normal blood sugar. Vitamin B6 is a known coenzyme for more than 100 enzymes involved in metabolic reactions in the body.
  • Vitamin B12 (Hydroxocobalamin or Methyl cobalamin)
  • L-Carnitine
  • B-Complex

References:

1. Best, C.H. and J.H. Ridout, The lipotropic action of methionine. J Physiol, 1940. 97(4): p. 489-94.
2. Jones, P.A. and D. Takai, The role of DNA methylation in mammalian epigenetics. Science, 2001. 293(5532): p. 1068-70.
3. Young, S.N. and M. Shalchi, The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain. J Psychiatry Neurosci, 2005. 30(1): p. 44-8.
4. Hongu, N. and D.S. Sachan, Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. J Nutr, 2003. 133(1): p. 84-9.
5. Corrado, F., et al., The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes. Diabet Med, 2011. 28(8): p. 972-5.
6. Solomon, L.R., Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment. Blood Rev, 2007. 21(3): p. 113-30.
7. Anthony Fardet and Jean-Michel Chardigny, Plant-Based Foods as a Source of Lipotropes for Human Nutrition: A Survey of In Vivo Studies, Critical Reviews in Food Science and Nutrition, 10.1080/10408398.2010.549596, 53, 6, (535-590), (2013).
8. Anthony Fardet, Jean-François Martin and Jean-Michel Chardigny, Caractérisation du potentiel lipotropique des produits alimentaires d’origine végétale, Cahiers de Nutrition et de Diététique, 47, 6, (291), (2012).
9. Mohsen Meydani, Dietary Effects on Detoxification Processes, Nutritional Toxicology,10.1016/B978-0-12-332602-7.50007-9, (1-39), (1987).
10. Colin C. Lucas and Jessie H. Ridout, Fatty livers and lipotropic phenomena, Progress in the Chemistry of Fats and other Lipids, 10, (5), (1970).
11. Leonora Mirone, Effect of vitamins in single dose on liver of mice on prolonged ethanol intake, Life Sciences, 5, 4, (317), (1966).
Elsawy, G., Abdelrahman, O., & Hamza, A. (2014). Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes. Journal of Human Kinetics, 40(1), 77–82. https://doi.org/10.2478/hukin-2014-0009
12. Green, R. A. L. S. on A. V. project, Allen, L., Bjørke-Monsen, A.-L., & Brito, A. (2017). Vitamin B12 deficiency. ReasearchGate, 3(17040), 1–20. https://doi.org/10.1038/nrdp.2017.40
13. Hongu, N., & Sachan, D. S. (2003). Carnitine and Choline Supplementation with Exercise Alter Carnitine Profiles, Biochemical Markers of Fat Metabolism and Serum Leptin Concentration in Healthy Women. The Journal of Nutrition, 133(1), 84–89. https://doi.org/10.1093/jn/133.1.84
14. Jain, S., & Singh, S. N. (2015). Effect of L-carnitine Supplementation on Nutritional Status and Physical Performance Under Calorie Restriction. Indian Journal of Clinical Biochemistry, 30(2), 187–193. https://doi.org/10.1007/s12291-014-0437-1
15. Kelly, G. S. (2011). MONOGRAPHS Pantothenic Acid. 16(3).
16. Kerns, J. C., Arundel, C., & Chawla, L. S. (2015). Thiamin Deficiency in People with Obesity. Advances in Nutrition, 6(2), 147–153. https://doi.org/10.3945/an.114.007526
17. Martinez, Y., Li, X., Liu, G., Bin, P., Yan, W., Mas, D., … Yin, Y. (2017). The role of methionine on metabolism, oxidative stress, and diseases. Amino Acids, 49(12), 2091–2098. https://doi.org/10.1007/s00726-017-2494-2
18. Padmavathi, S., & Vishwa, M. (2012). Effects of L-Carnitine (Neutraceutical) In Weight Management among Overweight and Obese Adults of Age between 20 – 45yrs – A Comparative Study in Chennai and Tirupathi. International Journal of Scientific and Research Publication, 2(9), 5.
Retrieved from http://www.ijsrp.org/research-paper-0912/ijsrp-p0984.pdf
19.Pekala, J., Patkowska-Sokola, B., Bodkowski, R., Jamroz, D., Nowakowski, P., Lochynski, S., & Librowski, T. (2011). L-carnitine--metabolic functions and meaning in humans life. Current Drug Metabolism, 12(7), 667–678.
20. Pooyandjoo, M., Nouhi, M., Shab-Bidar, S., Djafarian, K., & Olyaeemanesh, A. (2016). The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. Obesity Reviews, 17(10), 970–976. https://doi.org/10.1111/obr.12436
21. Spring, S., Singh, A., Zapata, R. C., Chelikani, P. K., & Pezeshki, A. (2019). Methionine restriction partly recapitulates the sympathetically mediated enhanced energy expenditure induced by total amino acid restriction in rats. Nutrients, 11(3), 1–21. https://doi.org/10.3390/nu11030707
22. Zheng, Y., Ma, A.-G., Zheng, M.-C., Wang, Q.-Z., Liang, H., Han, X.-X., & Schouten, E. G. (2018). B Vitamins Can Reduce Body Weight Gain by Increasing Metabolism-related Enzyme Activities in Rats Fed on a High-Fat Diet. Current Medical Science, 38(1), 174–183.
https://doi.org/10.1007/s11596-018-1862-9